Search on: GROWTH DIFFERENTIATION FACTOR 15 
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Descriptor English:   Growth Differentiation Factor 15 
Descriptor Spanish:   Factor 15 de Diferenciación de Crecimiento 
Descriptor Portuguese:   Fator de Diferenciação de Crescimento 15 
Tree Number:   D12.644.276.374.305
D12.644.276.954.300.915
D12.776.467.374.305
D12.776.467.942.300.915
D23.529.374.305
D23.529.942.300.915
Definition English:   A growth differentiation factor that is secreted in response to cell stress and in response to MACROPHAGE ACTIVATION. In addition growth differentiation factor 15 demonstrates a diverse array of biological properties including the induction of cartilage formation, the inhibition of hematopoietic progenitor proliferation, and the induction of neuronal migration. 
History Note English:   2009(1997) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   53127 
Unique Identifier:   D055436 

Occurrence in VHL:
 

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